Best Postbiotics Supplements in 2026: Top Picks for Gut Health & Immunity
By Hannah Emerson
Last Updated February 13, 2026
For the last few years, probiotics and prebiotics have been the talk of the town amidst wellness influencers, podcast bros, and almond moms everywhere, but there’s now another category gaining real traction: postbiotics supplements. These are the beneficial compounds left behind after probiotics break down food in your gut.
Unlike probiotics, which are live organisms, postbiotics are metabolic byproducts like short-chain fatty acids, enzymes, and peptides that can support immune function, soothe inflammation, and help your digestive system run more smoothly. The science hasn’t quite caught up with the hype, so there aren’t many products on the market yet, but these are the best postbiotics supplements that can round out your gut health routine.
The Bottom Line
Postbiotics aren’t as widely known as probiotics, but they’re quickly gaining traction for folks who care about digestion, immune balance, and overall gut wellness. The supplements below contain postbiotic ingredients that are backed by science and real consumer reviews.
Whether you want digestive comfort, immune support, or a daily gut health upgrade, these are some of the best postbiotics supplements you can buy right now.
1. Ritual Synbiotic+ 3-in-1
Ritual Synbiotic+
This popular supplement features 11b CFU of the world’s most studied probiotic strains, plus a pre- and post-biotic.
Best Overall Postbiotic + Prebiotic Blend
The 3-in-1 Synbiotic+ from Ritual combines clinically-studied prebiotics, probiotics and postbiotics for a simple solution to improve gut health. Plus, it’s infused with mint essence that makes the pill simple to take.
Their Made Traceable ideology ensures each product is rigorously inspected across traceability and sustainability standards, from ingredients sourcing to third-party testing to independent certifications.
Because microbiome research increasingly shows that synergy matters — feeding and supporting beneficial microbes while delivering their metabolic byproducts — products like this one are rising fast in search trends and customer preference.
Pros: Combines postbiotics, probiotics, and prebiotics in one formula, solid clinical backing
Cons: A bit pricier than basic capsules
2. Beam Biotic
If you prefer a versatile format, Beam offers a biotic powder that mixes easily into drinks or smoothies. It includes tribiotics — that’s prebiotics, probiotics, and postbiotics — and glutathione, a powerful antioxidant made from amino acids.
Mixed Berry and Citrus Lemonade flavors aren’t as versatile as an unflavored powder that could be mixed with any beverage, but we love that it’s made without artificial colors or sweeteners, and it’s great for those who prefer not taking pills.
Pros: Easy to mix, gentle on the stomach
Cons: On the pricier side
Beam Biotic
Mixed Berry or Citrus Lemonade turn gut health into a refreshing ritual.
3. Thorne Complete Biotic
If you’ve struggled with GI issues, you probably know Thorne. From their Gut Health Test to Digestive Enzymes and GI Relief, they’re a powerhouse in the gut health space. So, it comes as no surprise that they’re one of the first brands to get into the postbiotics market.
This Frosted Orange flavored powder is essentially an adult pixie stick. That’s right — you don’t even need to mix this bad boy with water, just pour straight onto your tongue. The unique trilateral combination offers a great solution for digestive discomfort and bloating.
Pros: Doesn’t require water, making it great for traveling, more affordable
Cons: Only comes in one flavor, has added artificial sweeteners
Thorne Complete Biotic
Get a prebiotic, probiotic, and postbiotic all in one stick. The fast-dissolving powder doesn’t even need to be mixed with water!
Is a Postbiotic Supplement Worth It?
If you’re already taking probiotics or eating fermented foods but still feel like your digestion could use a boost, it’s worth looking into swapping a regular probiotic for one that includes a post biotic. It’s not a quick fix, but many people notice results after a few weeks of consistent use.